Replenishing Night Cream Tx
Retinol isn’t enough anymore. This is where retinol meets replenishment. Wake-up to skin that looks smoother, more even, and visibly restored. Clinically proven to improve hydration, strengthen the barrier, and improve tone, lines, and wrinkles in 28 nights.
What You'll Notice:
Smoother, more refined-looking skin by morningSkin feels replenished, supple, and restoredFine lines appear softened, with a smoother, more polished surfaceSkin looks clearer, more uniform, with a naturally radiant finish
OBGYN Endorsed
Clinically Proven
Free ShippingWorks overnight, when skin is most responsive to renewal. This is your overnight treatment step, delivering controlled renewal while supporting the systems that keep skin balanced, hydrated, and resilient.
Rather than relying on retinol alone, it works across multiple aspects of skin at once. Most overnight treatments focus on one result. Skin doesn’t. This approach is designed to do more for skin overnight.
Encapsulated retinol smooths and refines through controlled overnight renewal, softening the appearance of fine lines and wrinkles. At the same time, plant-derived polysaccharides and lipid-rich botanical oils restore hydration and reinforce the skin barrier, so skin feels replenished, not depleted. Peptides support skin structure and elasticity for a firmer, smoother look while helping improve tone clarity for a more even, radiant appearance.
At the center of the formula is the AP² Longevity Platform, designed to help skin maintain balance, resilience, and consistency through hormonal changes. By morning, skin appears smoother, more refined, and more even, with a healthy-looking radiance. Skin feels replenished, supple, and well-rested.
Fragrance-free | Dermatologist-tested | OBGYN endorsed | Clinically Proven Results
1.7 fl oz / 50 ml
HIGH-PERFORMANCE ACTIVES
SATURATE | REINFORCE THE BARRIER
- Tsubaki Seed Oil – Velvety Nourishment
- Japanese Botanical Polysaccharides – Deeply Anchors Hydration
REFINE | CORRECT VISIBLE DAMAGE
- Encapsulated Retinol – Precision Renewal (Non-Irritating)
- Pea Peptide – Supports Density & Firmness
COMPOSE | STABILIZE THROUGH FLUX
WITH OUR PROPRIETARY AP² PLATFORM
- Adaptogenic Chaga – Resilience & Comfort
- Botanical Phytoestrogens – Balance & Coordination
- Peptides
Water (Aqua), Lauric/Myristic/Palmitic/Oleic Triglyceride, Pentaerythrityl Distearate, C12-18 Alkanoyl Glycerin/Sebacic Acid Copolymer, Camellia Japonica Seed Oil, C13-15 Alkane, Caprylic/Capric Triglyceride, Propylheptyl Caprylate, Dimethicone, Cetearyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Butylene Glycol, Acetyl Tetrapeptide°9, Inonotus Obliquus (Mushroom) Extract, Punica Granatum Fruit Extract, Acetyl Tetrapeptide-11, Papaver Rhoeas Petal Extract, Ziziphus Jujuba Fruit Extract, Retinol, Pisum Sativum (Pea) Seed Extract, Angelica Acutiloba Root Extract, Trifolium Pratense (Clover) Leaf Extract, Cimicifuga Racemosa Root Extract, Lithospermum Erythrorhizon Root Extract, Dioscorea Japonica Root Extract, Sodium Hyaluronate, Achillea Millefolium Extract, Algin, Glycerin, Ceteareth-20, Sodium Stearoyl Glutamate, Synthetic Fluorphlogopite, Sodium Polyacrylate, Titanium Dioxide (CI 77891), Propanediol, Caprylyl Glycol, Phenylpropanol, Polysorbate 20, Dimethyl Isosorbide, Glycine Soja (Soybean) Oil, Pentylene Glycol, Silica, Glyceryl Polyacrylate, Pullulan, Benzyl Alcohol, Carbomer, Xanthan Gum, Potassium Sorbate, Sodium Benzoate, Acacia Senegal Gum, Tocopherol, Propylene Glycol Alginate, Citric Acid.
Fragrance-free
Hormone-free
Dermatologist tested
Clinically proven results
Your most resilient skin, activated by morning.
SMOOTHER | STRONGER | VISIBLY RESTORED
Lines appear softened. Skin feels replenished, supported, and deeply restored. Finally, skin is getting what it needs. All the results of retinol, plus more, without the downside. A more complete way to treat skin overnight.
the benefits
SMOOTH + RENEW: Encapsulated retinol
SMOOTH + RENEW: Encapsulated retinolRefines texture and supports visible renewal for smoother, more refined-looking
skin.
STRENGTHEN + FIRM: Advanced peptide complex
STRENGTHEN + FIRM: Advanced peptide complexImproves the look of skin structure and elasticity for firmer, more resilient-looking
skin.
CORRECT + ILLUMINATE: Tone-correcting peptides + plant actives
CORRECT + ILLUMINATE: Tone-correcting peptides + plant activesImproves tone clarity for a more uniform, radiant-looking complexion.
NOURISH + REPLENISH: Tsubaki oil + bio-polysaccharides (including sacran)
NOURISH + REPLENISH: Tsubaki oil + bio-polysaccharides (including sacran)Restores moisture and helps skin retain hydration with sacran, a Japanese algae known for its exceptional ability to bind water. Skin feels supple, replenished, and not depleted.
ADAPT + SUPPORT: AP² Longevity Platform
ADAPT + SUPPORT: AP² Longevity PlatformHelps skin maintain balance and resilience through ongoing hormonal and environmental change. Skin appears stronger, more consistent, and healthy-looking.
The Morning Reveal: Witness the Shift
I can’t say enough about how much I love the Replenishing Night Cream. My skin had been looking dull and tired, and nothing seemed to make a lasting difference. I started waking up with softer, fresher-looking skin. Now, a month in, I can see a healthy glow, my skin feels plumper, and even my fine lines look smoother. I'm so pleased with the results and can't wait to delve into the rest of the Sum Of All product line.
Christine M.
Powered by the AP² Longevity Platform
Our proprietary complex at the core of every formula
A curated complex of adaptive peptides, phyto-actives, and barrier-supporting ingredients designed to help skin maintain collagen integrity, resilience, and visible vitality through hormonal change.
One platform, every product.
HIGH-PERFORMANCE ACTIVES
A patent-pending blend of Adaptogens, Phytoestrogens, and Peptides. Together, they help reinforce the skin’s structure, hydration, and resilience during hormonal change—supporting the source, not just the symptoms.
Advanced delivery system for gentle overnight renewal — with minimized irritation and clinically proven, deeper skin penetration. In a clinical study, up to 99.5% of retinol was absorbed into the skin within 6 hours, ensuring longer-lasting results where they matter most.
Soothe, oxygenate, and visibly revitalize the skin while helping lock in lasting hydration.
A rich source of antioxidants and omega fatty acids that deeply nourishes, softens, and strengthens the skin barrier without feeling heavy or greasy.
Lightweight botanical oils that help fortify the skin’s barrier, deeply nourish, and maintain lasting moisture balance.
How to use
01Preparation
Use in the evening on clean, dry skin, 2–3 times per week.
02Application
Apply a thin layer to face and neck, avoiding the eye area.
03Routine
For optimal results, layer over Overnight Resurfacing Serum Tx or Collagen Boosting Serum Tx. Always apply SPF the following morning.
What customers are saying
Frequently asked questions
Yes—encapsulated retinol for effective smoothing with minimal irritation.
No. It’s balanced with omega-rich Tsubaki oil and hydrating ingredients to nourish while it smooths.
Yes. It’s specifically formulated to support hormonally affected skin and barrier repair overnight.
Yes. Use nightly as tolerated, or alternate with Overnight Resurfacing Serum depending on your needs.
Smoother texture, softer lines, and improved hydration within 2–4 weeks of consistent use.
Night cream is formulated to aid your skin's natural repair process during sleep. Your skin acts differently at night, it's more accepting of moisture and active ingredients, so night creams are usually richer and more nourishing than daytime moisturizers.
A quality night cream hydrates, minimizes fine lines, and strengthens the skin's barrier after a long day. Our Replenishing Night Cream TX goes beyond, offering deep moisture combined with encapsulated retinol and bioactives ideal for skin at midlife.
Absolutely, especially if you experience dryness, tightness, or dullness in the morning. A high-quality night cream can help balance and refine skin texture over time, all while you sleep.
The perfect night cream is the one that meets your current skin needs. Replenishing Night Cream TX is specifically crafted to support skin affected by hormonal changes and age-related dryness, utilizing the AP² Complex, plant-based lipids, retinol, red algae, and more.
There isn't a one-size-fits-all "best," but seek out formulas that deliver both hydration and targeted care without causing irritation. Ours offers comfort and conditioning, working diligently overnight.
For hydration, renewal, and ingredients that honor skin undergoing changes, our night cream could be the perfect addition to your evening regimen. It's rich yet breathable, active yet gentle.
Yes, though we suggest gradually introducing any retinol-based product if you're new to it. Begin with every other night and adjust as necessary. Pay attention to your skin's response and adapt accordingly.
Unlike daytime moisturizers, night creams are more nourishing and incorporate activities that are best used without sun exposure. Our formula also contains blue-green algae molecules and peptides that work overnight to leave your skin feeling rejuvenated by morning.