The Sum of Ancient Wisdom + Modern Innovation
Skincare that meets your biology where it is. Rooted in hormonal dermatology, powered by clinically validated ingredients.
Menopause & Your Skin
As estrogen declines during perimenopause and menopause, so does the skin’s ability to produce and retain collagen, hydration, and lipids. The result? Thinner skin, loss of elasticity, dryness, increased sensitivity, and slower repair. We formulate skincare that works with (not against) your body’s natural changes, helping your skin regain its strength, structure, and glow.
Subtle shifts begin, less hydration, more sensitivity. Support barrier strength and early collagen loss.
Estrogen drops dramatically. Skin becomes thinner, more fragile, and less elastic. Prioritize collagen, lipid support, and inflammation control.
These changes stabilize. Skin needs ongoing structural support, hydration, and protection from oxidative stress.
Inside the AP² longevity platform
A hormone-conscious blend of plants and peptides designed to rebuild, rebalance, and restore.
Adaptogens
Help the skin recover from stress, calm inflammation, and restore visible radiance.
Included in the complex: Chaga Mushroom
Phytoestrogens
Support skin that’s affected by estrogen loss—helping restore volume, tone, and elasticity.
Included in the complex: Red Clover
Peptides
Signal the skin to rebuild its own collagen and strengthen the dermal structure.
Included in the complex: Biomimetic Collagen Peptides
Key Ingredients
​​Explore the clinically backed ingredients we rely on most:
A superior hydrator that holds up to 500x its weight in water, delivering deeper, longer-lasting moisture than traditional hyaluronic acid.
Smart UV-activated antioxidants that brighten skin and reinforce daily defense against environmental stressors.
Antioxidant-rich red algae helps calm visible irritation, defend against environmental stressors, and promote a more radiant, even-toned complexion.
Soothe, oxygenate, and visibly revitalize the skin while helping lock in lasting hydration.
A powerhouse ferment rich in amino acids, vitamins, and antioxidants — clinically shown to support collagen and elastin renewal, strengthen the skin’s natural barrier, and defend against visible signs of oxidative stress.
A rich source of antioxidants and omega fatty acids that deeply nourishes, softens, and strengthens the skin barrier without feeling heavy or greasy.
OBGYN Approved
Hormonal dermatology isn’t niche. It’s necessary. We collaborate with dermatologists, OBGYNs, and clinical researchers to ensure our products work in harmony with your biology, not just your surface concerns. No gimmicks. No empty claims. Just hormone-conscious skincare that’s thoughtfully designed and rigorously tested to target the visible effects on skin.
I have been absolutely thrilled with the product and the results... I would recommend Sum Of All without reservation for women who want RESULTS from their skincare regimen.
Dr. Jennifer L. Anderson, MD