Overnight Resurfacing Serum Tx
Midlife skin is just as delicate, and it still needs resurfacing. This gentle overnight serum takes away what dulls and gives back what nourishes, for skin that looks smoother and brighter with every use.
Reveal without regret.
What you'll notice:
Right away: Skin feels softer and smoother, with a refreshed glow.Over time: A more refined texture, a brighter, more even tone, and softer-looking fine lines.Three kinds of gentle exfoliation, cushioned by replenishing hydration.
Resurfacing that gives back, in one evening step.
OBGYN & Dermatologist Endorsed
Clinically-Tested Ingredients
Free Shipping“I tell my patients to put the scrubs away. This is how midlife skin should be resurfaced: gently, overnight, with something given back.”
Dr. Shari F. Topper, Board-Certified Dermatologist and Sum of All Co-Chief Medical Officer
Water (Aqua), Caprylic/Capric Triglyceride, Arginine, Dimethicone, Cetearyl Alcohol, Glycerin, Pentaerythrityl Distearate, Tremella Fuciformis Polysaccharide, Glycolic Acid, Propanediol, Hydrolyzed Elastin, Hibiscus Rosa-Sinensis Flower Extract, Chlorella Ferment, Punica Granatum Fruit Extract, Ananas Sativus (Pineapple) Fruit Extract, Papaver Rhoeas Petal Extract, Ziziphus Jujuba Fruit Extract, Trifolium Pratense (Clover) Leaf Extract, Cimicifuga Racemosa Root Extract, Lithospermum Erythrorhizon Root Extract, Dioscorea Japonica Root Extract, Inonotus Obliquus (Mushroom) Extract, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Vegetable Oil, Hibiscus Sabdariffa Flower Extract, C13-15 Alkane, Ceteareth-20, Sodium Stearoyl Glutamate, Sodium Polyacrylate, Propylene Glycol, Phenylpropanol, Caprylyl Glycol, Polysorbate 20, Dimethyl Isosorbide, Tocopheryl Acetate, Dimethicone/Vinyl Dimethicone Crosspolymer, Xanthan Gum, Hydrolyzed Rhodophyceae Extract, Hydrogenated Vegetable Oil, 1,2-Hexanediol, Euphorbia Cerifera (Candelilla) Wax
Size: 1.0 fl oz / 30 ml
What it is: Your renewal step for midlife skin. A gentle overnight resurfacing serum that lifts away dullness and replenishes hydration at the same time, with our AP² Longevity Platform at its core.
Best for: Rough or uneven texture · Dullness · Uneven-looking tone · Fine lines · Dryness
Texture: A silky, lightweight serum.
When to use: Evenings, two to three nights a week on average, from once a week up to every night as tolerated. Use Collagen Boosting Serum Tx on the other nights.
Formulated: Fragrance-free · Made in the USA · Dermatologist- and OBGYN endorsed
A return to Optimal Skinstate.
Overnight Resurfacing Serum Tx
Fragrance-free
Clinically-tested Ingredients
Made for midlife skin
Renewal slows down. Your glow doesn't have to.
As estrogen declines, skin sheds dull cells more slowly and holds less moisture, so texture turns rough and fine lines look deeper. Skin also becomes thinner and more reactive, so harsh peels and scrubs can leave it worse off.
It's biology, and biology can be supported. Overnight Resurfacing Serum Tx gently lifts away dull buildup while it nourishes skin and supports its barrier. Skin feels softer the next morning and looks smoother, brighter and more even with continued use.
Your freshest skin, renewed while you rest.
RESURFACE
Lifts away dullness, gently. Slow-release glycolic acid, hibiscus flower acids and pineapple enzyme work in different ways to loosen and clear dull surface cells, for skin that looks brighter and clearer.
REPLENISH
Cushions skin while it renews. Hydrolyzed elastin helps skin feel softer and more supple, tremella mushroom and red algae hold moisture where skin needs it, and chlorella delivers amino acids, vitamins and minerals for a comfortable feel after exfoliation.
RESTORE
Keeps skin resilient through change. Powered by our AP² Longevity Platform of adaptogens, phytoestrogens and peptides, it supports skin's barrier and comfort so you can resurface without starting over.
What to look forward to
THE
Next morning
Skin feels softer and smoother, with a
fresh, rested glow.
WITH
Continued use
Texture looks more refined, tone looks
more even and fine lines look softer.
BEHIND
The glow
In lab research, tremella helped skin cells make more of their own hyaluronic acid and procollagen.²
"My mother is an artist, and I grew up watching her work. Before she ever picked up a brush, she prepared her canvas. I think of skin the same way: no serum or foundation can give its best on skin that's dull and uneven.
Midlife skin needs that priming more than ever, but it's also more reactive. So this serum resurfaces gently with slow-release glycolic acid, hibiscus flower acids and pineapple enzyme, while elastin, red algae and tremella give back what skin needs.
One thing to know: it's fragrance-free, so you'll notice the natural scent of the ingredients. Some women don't mind it, and some take time to get used to it. I chose not to mask it, because fragrance is one of the most common irritants for midlife skin.
My tip: prime your canvas two or three nights a week."
Powered by the AP² Longevity Platform
Our proprietary complex at the core of every formula
A curated complex of adaptive peptides, phyto-actives, and barrier-supporting ingredients designed to help skin maintain collagen integrity, resilience, and visible vitality through hormonal change.
One platform, every product.
High Performance Actives
Glycolic Acid
A slow-release form of the gold-standard alpha hydroxy acid. Bound to the amino acid arginine, it's released gradually into skin, and we added extra arginine to buffer it even further, for gentle, steady resurfacing with less sting, revealing smoother, brighter, more even looking skin over time.
Pineapple Enzyme
A fruit enzyme that softly dissolves surface buildup, refining rough texture and dullness without over-stripping.
Hibiscus Flower Acids
Flower acids from hibiscus, a natural blend of gentle fruit acids that renew skin's surface while helping it hold moisture, for skin that looks more radiant, smooth and clear.
Hydrolyzed Elastin
A replenishing hydration technology that cushions skin with lasting moisture for softer, smoother, more refreshed-looking skin.
Red Algae
A marine botanical rich in minerals and moisture-binding sugars that helps skin stay hydrated and comfortable while it renews.
Tremella Mushroom
A naturally moisture-rich mushroom that cushions skin with hydration, so it feels soft and comfortable while it renews. It also naturally contains amino acids that are building blocks of collagen. In lab studies, tremella helped skin cells make more of their own hyaluronic acid and procollagen.²
Chlorella
Fermented microalgae rich in protein, vitamins, minerals and amino acids. Like tremella and hibiscus, it naturally contains amino acids that are building blocks of collagen, for a soft, replenished feel after resurfacing.
How to Use
01Apply
In the evening, smooth one to two pumps over clean, dry skin across your face and neck, avoiding the eye area.
02Absorb
Let it absorb fully before your next step. There's nothing to rinse: it works while you sleep.
03Layer
Follow with Replenishing Night Cream Tx, then Flash Effect Eye Cream Tx. The next morning, always finish with broad-spectrum SPF.
How often: Most women use it two to three nights a week. Adjust to your skin: as little as once a week, or up to every night as tolerated. On the other nights, use Collagen Boosting Serum Tx
Wake up to skin that looks rested, refreshed and ready.
What Customers Are Saying
Frequently Asked Questions
Estrogen helps skin stay hydrated and renew on a steady rhythm. As it declines, skin sheds surface cells more slowly and holds less moisture, so dull, dry cells build up. That shows as rough texture, dullness and fine lines that look deeper. Overnight Resurfacing
Serum Tx from Sum of All was made for this change.
It gently lifts away dull surface buildup while it nourishes skin and supports its barrier overnight. Glycolic acid, flower acids and pineapple enzyme refine the surface, while hydrolyzed elastin, tremella and chlorella cushion skin with moisture and suppleness. Skin feels softer the next morning, and with continued use it looks smoother, brighter and more even.
Many exfoliants only take away. Overnight Resurfacing Serum Tx removes dull surface buildup while it delivers nutrients and hydration and supports skin's barrier with Sum of All's patent-pending AP² Longevity Platform. That balance makes it right for midlife skin, which is often drier and more reactive. It's dermatologist- and OBGYN endorsed.
Midlife skin tends to be thinner, drier and more reactive, so gritty scrubs and aggressive peels can leave it irritated. Overnight Resurfacing Serum Tx offers a gentler approach: glycolic acid, hibiscus flower acids and pineapple enzyme lift away dull buildup while the formula nourishes skin and supports its barrier.
It's fragrance-free and formulated to be gentle on midlife skin, which can become more reactive during menopause. Most women use it two to three nights a week, and you can go as low as once a week if your skin is very sensitive.
Most women notice softer, smoother-feeling skin and a fresh glow the next morning. With continued use, texture looks more refined and tone looks more even.
Yes. Texture and dullness often start to shift in perimenopause as estrogen fluctuates. Adding gentle resurfacing then helps skin stay smooth and bright through the transition and beyond.
In the evening, smooth one to two pumps
over clean, dry skin on your face and neck, avoiding the eye area. Let it absorb, then follow with Replenishing Night Cream Tx and Flash Effect Eye Cream Tx.
Most women use it two to three nights a week. Adjust to your skin: as little as once a week, or up to every night as tolerated. On the other nights, use Collagen Boosting Serum Tx.
No. It's a leave-on treatment designed to
work while you sleep.
Yes. As with any exfoliant, use broad-spectrum SPF every morning, especially the morning after you use Overnight Resurfacing Serum Tx.
A light tingle can happen as skin gets used to resurfacing. Use it fewer nights a week, even just once, and if discomfort continues, pause and check with your provider.
On average, one 1.0 fl oz / 30 ml bottle lasts 2 to 3 months, depending on how often you use it. With Subscribe & Save, a new bottle arrives every 3 months, so your ritual never misses a beat.
Yes. On nights you use it, apply Overnight Resurfacing Serum Tx first, let it absorb, then layer Replenishing Night Cream Tx, Sum of All's encapsulated retinol night cream, on top. They're designed to work together. If you use a prescription retinoid, follow your provider's
guidance on how to layer them.
Use vitamin C in the morning. On nights you
use Overnight Resurfacing Serum Tx, skip other exfoliating acids or scrubs so
skin isn't over-exfoliated.
Yes. It contains no estrogen or other added hormones, and its phytoestrogens are plant compounds, not hormones. Hormone therapy works from within, and skincare supports skin from the outside. If you have questions about your treatment, talk with your provider.
Pause it before and after in-office treatments, and follow your provider's guidance on when to resume.